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Quick Facts: Paid Clinical Trials for Smokers Actively recruiting US smoking cessation studies (July 2026): 111 (ClinicalTrials.gov) Typical compensation: $25$100 per completed visit, often with completion or verified-abstinence bonuses Cost to participate: $0 study treatment and visits are covered by the sponsor Growing area: vaping and e-cigarette cessation studies are also recruiting Find one near you: Browse paid clinical trials by state or see drug addiction clinical trials 2026 Smoking Cessation Research Updates First new quit-smoking drug in 20 years is close: Cytisinicline, tested in the ORCA-2 and ORCA-3 trials with more than 2,000 participants, received an FDA Complete Response Letter in June 2026 over third-party manufacturing issues the agency cited no concerns with its effectiveness or safety

By Blake Harper 23 April 2025 Nearly 23.6% of people in the United States are smokers

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