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Then, in January, 2005, under the regime of Silvio Berlusconi and his anti-smoking health minister, Girolamo Sirchia, an extraordinary thing happened

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Besides the limitation of lacking information on the frequency and dosage of ICS use in the lung tissue cohorts, another limitation of our study is that ICS use may have contributed to the heterogeneity in responses in vitro, even though cells had been cultured for 23 weeks before experimentation

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