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Ensure that defendants are aware of this in plea negotiations

Smokers also have a greater risk of heart attack, respiratory illness (emphysema, COPD, pneumonia), high blood pressure, stroke, heart disease, peripheral vascular disease, and aortic aneurysms

Upon activation by the stimuli of external harmful substances, they promote the expression of inflammatory cytokines and actively participate in the process of airway inflammation via secretion of inflammatory mediators, cytokines and growth factors (9)

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[3] The Ardath Tobacco Company Limited was originally located at 62 Leadenhall Street in London and called La Casa de Habana (The House of Havana) until 1895, when it changed its name to the present day version