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& Wang, Y.-S

As citrullination is considered one of the crucial steps in the development of RA, and also as ACPAs seem to be involved in the progression of RA, new pharmaceutical agents targeting PADs have been investigated: PAD inhibitors including F-amidine (the most potent known inhibitor), paclitaxel and 2-chloroacetamidine [40]

When considering PEG (price-earnings growth ratio), BTI is more attractive due to its reduced-risk business having high growth potential