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Racial/ethnic heterogeneity of smoking on risk In our primary analysis of differing associations of smoking variables with pancreatic cancer risk by race/ethnicity, there was no significant difference in the association between pack-years smoked and pancreatic cancer risk across racial/ethnic groups [ p LRT = 0.41 on 4 degrees of freedom (df)] (Supplementary Table 1)

The data were logarithmized (ln (SCR+1)) to normalize the distribution (Venables and Christie, 1980)

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1063 practising optometrists completed the online survey between 12 February and 22 March 2019