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The areas in which there is the most clinical evidence to support the use of CBD are in the treatment of anxiety (positive data in 7 uncontrolled studies and 17 randomised controlled trials (RCTs)), psychosis and schizophrenia (positive data in 1 uncontrolled study and 8 RCTs), PTSD (positive data in 2 uncontrolled studies and 4 RCTs) and substance abuse (positive data in 2 uncontrolled studies and 3 RCTs)

PloS one 8(3):e58516

The nicotine in a tobacco blunt wrap can also add its own effect on top of the cannabis flower

Smoking just a couple of cigarettes a day raises cardiovascular disease risk by more than 50%, a much larger increase than would be expected based on the small number of cigarettes

Instead, use a soft, dry cloth to wipe it down and a very small amount of rubbing alcohol to get stubborn spots cleaned