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Early in 1994, a study 14 analyzed 454 patients with oral carcinoma and found that 60% of those with oral carcinoma smoked and over 95% of neoplasms were squamous cell carcinoma, while another study 15 in 1999 stressed the significance of tobacco in the progress of oral epithelial dysplasia (OED) in a large number of European patients
But health officials still have not identified the cause.
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