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Analysis of data from the 2014-2015 Tobacco Use Supplement to the Current Population Survey found that those who started smoking before the age of 18 were 2.15 times as likely to become nicotine dependent in their lives, compared to those who started smoking at age 21 or older

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Nicotine use is associated with a variety of sleep problems including insomnia, reduced REM sleep and inability to stay asleep

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