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Its teams have engaged with the FDA on the substantial-equivalence process for cigarettes and smokeless tobacco for a decade and, more recently, for its cigar business

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PTFE flasks used in digestion underwent a rigorous cleaning process consisting of washing with detergent, a 24 h soak in 5 M HNO3, rinsing with detergent, distilled water, and deionized water, followed by oven-drying to prevent cross-contamination

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