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craving) to take the drug, difficulties in controlling its use, persisting in its use despite harmful consequences, a higher priority given to drug use than to other activities and obligations, increased tolerance, and sometimes a physical withdrawal state"

They additionally note that, since AhR ligands are also found in pollutants and industrial chemicals, the findings may carry wider public health significance

Retrieved 26 March 2018

Yet, their cardiovascular health risks are still unclear

Regulatory discussions that began in 2016 had stalled for nine years amid industry opposition, but legislative debate was reignited after the harmful effects were confirmed