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The highly addictive component in both tobacco and e-cigarettes, nicotine causes tissue inflammation, which can lead to injury

[144] A 2014 Cochrane review was unable to make conclusions regarding acupuncture as the evidence is poor

Constantinos Sioutas While tobacco smoke contains high levels of polycyclic aromatic hydrocarbons cancer-causing organic compounds the level of exposure to these substances was reduced to almost zero in secondhand e-cigarette smoke, due to the fact that they do not burn organic material the way old-fashioned cigarettes do

Jayawardhana, Ray