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While primarily targeting cigarettes, it reflects a broader long-term strategy to phase out nicotine use entirely

However, the -KgCN concentration increased more than 100-fold over compared to endogenous concentrations

Yeager Aeronca LW, William F

Secondly, smoking cessation intention due to the assumed GWLs on cigarette package was just the attitude of smokers but not the actual behavior change, which impeded the observation of real effect, so implementing an intervention and follow-up study would be a major step forward to evaluate the actual effect of GWLs as tobacco control measure

The analysis defined a cardiovascular disease event as any self-reported diagnosis of heart attack or bypass surgery, heart failure, other heart conditions or stroke in the previous 12 months