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The chart below summarizes some common physical changes

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In addition to toxicant exposure, cannabinoids such as 9-tetrahydrocannabinol (THC) and cannabidiol (CBD) interact with the endocannabinoid system, which plays a key role in regulating DNA damage and repair, mitochondrial function, and cellular senescence 14,15

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By that logic, a host of products aimed at achieving a healthier lifestyle, ranging from motivational calendars (an example Siegel mentions) to exercise equipment, would qualify as drugs under the Food, Drug, and Cosmetic Act