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When nicotine stimulates those nerves, a few reactions can occur: The diaphragm becomes briefly irritated and spasms Nicotine may stimulate stomach acid production, which can irritate nearby nerves Swallowing increases, sometimes trapping air in the stomach The body responds to the effects of nicotine by activating reflexes tied to breathing Public health groups tied to disease control often point out that nicotine affects several systems at once

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Frank Lester, a spokesman for Reynolds America Inc., said his company upped the price of cigarettes in response to the tax and to remain competitive with industry leader Phillip Morris