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The potential association between cigarette smoking and prostate cancer, attributed to exposure to harmful chemicals such as tar, arsenic, cadmium, butane, acetic acid, acetone, formaldehyde, ammonia, lead, and carbon monoxide, is illustrated in Table 2
These changes were accompanied by significant taxonomic shifts, notably the depletion of health-associated, nitrate-reducing genera like Haemophilus and Neisseria and the enrichment of pro-inflammatory anaerobes such as Atopobium and Veillonella