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The Sin Tax Reform Law of 2012 increased excise taxes to PhP30 (054 USD) and created a single-tier tax rate for all tobacco products

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Furthermore, we measured the expression of biomarkers of ferroptosis using mouse tissues and found ENDS increased expression of ferroptosis-specific markers including Transferrin Receptor/CD71 (39) and ACSL4 (40) and reduced the expression of GPX4 ( Figure 6B ), the loss of which is reported required for ferroptosis (41)

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