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We know what cigarettes do to the lungs, said study author Giselle Revah, MD, a cardiothoracic radiologist and assistant professor at the University of Ottawa in Ottawa, Canada

To dispel the possibility that this induction of osteoclast differentiation and inhibition of osteoblast differentiation was solely the result of induction of inflammatory mediators in the bone marrow, we measured TNF levels in the bone marrow adherent cells treated with CSE at different concentrations

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