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It is important to note that while sporadic reports of severe lung disease associated with using e-cigarette products have been reported since 2012 [10,11,12,13,14], patients from these earlier reports less frequently reported cannabis use, unlike the 2019 outbreak [10]

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The study used B4Crry, a single-chain variable fragment (scFv) antibody derived from the B4 IgM monoclonal antibody (a self-reactive pathogenic natural IgM antibody)