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Data were then subjected to principal component analysis (PCA), hierarchical clustering analysis (HCA), partial least squares-discriminant analysis (OPLS-DA) using SIMCA-P version 13.0 software package (Umetrics, Umea, Sweden)

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Vaping is also technically less harmful than cigarettes, as they do not contain as many toxic chemicals: 1 cigarettes can contain a mixture of about 7,000 chemicals including tobacco, which is not found in most vaping cartridges

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