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These are not present in the vapour produced by an e-cigarette, so vaping offers a safer option for nicotine delivery compared to smoking

Aside from the health consequences of vaping, these devices may also malfunction and explode, causing severe injuries

Statistical analysis Subjects were assigned to the PK population set (PK set) if they completed the use of the study product, had data for the critical time points in the plasma nicotine concentrationtime profiles, did not use a concomitant medication that rendered the concentration profile unreliable, and did not violate the protocol (major protocol deviation) in a way that might invalidate or bias the PK results

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