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Furthermore, health warnings detail harmful substance content

Morris Coats, "A Note on Estimating Cross-Border Effects of State Cigarette Taxes" National Tax Journal, December 1995, 573

The most common explanation goes like this: on the battlefield, if a military surgeon was caring for a gravely wounded soldier and amputation of a leg or arm was necessary, the operation took place without any anesthesia, except maybe a drink of alcohol

No, pipe tobacco can be stored in a sealed pouch or jar, though proper storage is still important to maintain freshness.