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Statements Author contributions Concept and design: KW, MI, SS, KS, JC, literature search: KW, MI, SS, data acquisition: MI, SS, NP, PG, data analysis: KW, article preparation: KW, article editing: KW, MI, SS, KS, NP, PG, JC, article review: KW, MI, SS, KS, NP, PG, JC This article has been read and approved by all authors

We now have E-Cigarettes in a whole host of flavours and strengths, and millions of people have been able to finally get off the cigarettes thanks to them

Kenealy, T

Smoking has been linked to both weight loss and gain

Questions for FDA to address in final guidance: What is the public health and ethical justification for imposing far higher barriers to entry to safer nicotine products, while there are thousands of highly dangerous combustible products widely available