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Biological factors involve neurochemical changes, physical dependence, and genetic susceptibility
The high attrition rate of 61% at follow-up created a non-representative sample that may limit generalizability, with retained participants being older, less likely to be from England, more likely to be from an identified majority group, and having lower education compared to those lost to follow-up
Obviously, it would be great for everyone involved if this plan were successful in getting him back on track
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