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Shadel noted that most of the studies on IQOS have been conducted by Philip Morris, and much more research is needed by independent researchers who are not associated with the company to determine the safety of the product

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The researchers found that despite not being cancerous, more than nine out of every 10 lung cells in current smokers had up to 10,000 extra genetic changes mutations compared with non-smokers, and these mutations were caused directly by the chemicals in tobacco smoke

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