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Smokers can use this method in daily life when they feel the craving for tobacco or to prevent these problems after stopping smoking for some time
The strongest evidence for the self-medication hypothesis comes from the neurophysiological findings of sensory processing deficits in pre-pulse inhibition and suppression of P50-evoked potential, and abnormalities in anti-saccadic eye movement tests (Kumari Reference Kumari and Postma2005)