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Tobacco smoke contains nicotine and other chemicals, such as cadmium, that can affect central nervous system structures [69] or stimulate expression of pro-inflammatory molecules resulting in peripheral and central sensitization which can contribute to the development of headache pain [7072]
Although, the smoking culture impacts all people with mental illness, SZ patients are particularly likely to be exposed, as they receive treatment largely in institutions and mental health settings (157)
It was also revealed that tobacco consumption was notably common among the poor, less educated, scheduled castes, and scheduled tribe populations
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