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A small percentage of people (under 7 percent) get oral cancers from no identified cause, says the Oral Cancer Foundation

Smoking appears to have both causal relationships and possible synergistic interactions with other major risk factors for coronary heart disease, including hyperlipidemia, hypertension, and diabetes mellitus [ 54 ]

Adolescents are quite vulnerable to the side effects of chronic alcohol abuse as their brains are still developing

But perhaps the biggest complication is that e-cigarettes are extremely new and so the most important research hasn't had time to be conducted

Paul Macey, an associate professor at UCLAs School of Nursing