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With no strong evidence of harm related to short-term smoking abstinence, the Society for Perioperative Assessment and Quality Improvement (SPAQI) and the American Society of Anesthesiologists (ASA) Taskforce strongly recommend that patients be advised to quit smoking as soon as possible irrespective of surgery timing

Sirtuin 1 (SIRT1) has been involved in decision making over cellular senescence or apoptosis in lung diseases including COPD and cancer [53, 90]