The chronic toxic effect on the respiratory system by the generated metabolites would induce sustained and chronic damage to the respiratory system, causing damage of the vascular endothelial cells and increased coagulation of the blood vessels as well as reduced blood volume in skeletal muscles
The structural damage may result in various symptoms, including chronic coughing, increased mucus, and shortness of breath
Taylor & Francis: 573585
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Solar cheilitis is more common in adults and the risk increases with age