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Furthermore, most of the data assessing cigarette smokings effect on IBD and treatments are primarily from uncontrolled observational studies where it is difficult to account for, much less eliminate, the effects of residual confounders

Cigarettes are still cheap, freely promoted and available on every street

That might change with a higher ambient and/or lower humidity

Literature search methodology This article is designed as a narrative review aiming to integrate current evidence on smoking-induced microbial dysbiosis and its systemic implications

and white visually links these two colors, maintaining a sense of harmony