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If the BMD as preferred toxicological threshold for MOE assessment is unavailable, no observed effect levels (NOEL), no observed adverse effect levels (NOAEL) or lowest observed adverse effect levels (LOAEL) may be applied

E-liquids also contain propylene glycol and vegetable glycerin, listed as GRAS (generally regarded as safe) by the FDA

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Other studies had similar positive findings

Moreover, there has been growing concern over vaping-related lung injuries, which can lead to severe short-term health outcomes, including immediate lung damage and risk for respiratory failure