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Altria executives said they would submit a PMTA for On

METHODS Study design The present study was an open-labeled, two-arm pilot RCT (allocation ratio 1:1)

Nicotine uptake (AUC) at 15 and 240 min for UB cigarette was 147 and 1058 ng x min/mL, respectively, whereas for nicotine gum, it was 4.79 and 464 ng x min/mL, respectively

NRT is a licensed medication with minor side effects, which is recognised as an essential medicine by the WHO.[12] Understanding of the relative risk of NRT compared to smoking among smokers remained poor up to 2023 (Figure 28)

One factor impacting the decision is the decline in cigarette sales, which have dropped by 26% since 2019