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[97] study indicated that co-cultured human pulmonary vascular endothelial cells (HPVECs) with different concentrations of CSE (0%, 0.1%, 1% and 10%) significantly promoted cell apoptosis, increased caspase-3 activity, upregulated Bax expression, decreased Bcl-2 expression, and increased expression of the lncRNA MEG3

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This one also feels to have a strong nicotine content

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